Subscribe to get Updates
Nootropedia
No Result
View All Result
  • Nootropics
    • Racetams
    • Natural
    • Cholinergics
    • Unique Blends
  • Brain & Body Support
    • Cognitive Enhancers
    • Food & Nutrition
    • Anti-Oxidants
    • Nutrients & Minerals
    • Hormone Support
    • Inflammation & Immune
    • Fitness & Movement
  • Mood
    • Stress Relief
    • Herbs & Plants
    • Relaxation Strategies
  • Healthy Aging
    • Memory
    • Cellular Health
  • Alternative Solutions
    • Essential Oils
    • Anxiety
    • ADHD
    • Sleep Aids
  • Blog
    • Comparisons
    • Guides
    • How To
HealthNews
No Result
View All Result
HealthNews
No Result
View All Result

Vinpocetine

July 4, 2019
This post may contain affiliate links.
Vinpocetine
621
VIEWS
Share on FacebookShare on TwitterShare on PinterestShare on Linkedin

Quick Navigation

  • Summary
  • Also Known As
  • Editors’ Thoughts on Vinpocetine
  • Benefits of Vinpocetine
    • How Does Vinpocetine Work?
  • Side Effects of Vinpocetine
  • Vinpocetine Dosage
  • How and Where to Buy Vinpocetine
  • Selected Community Experiences

Summary

With a name like Periwinkle, it might be hard to take this neuroprotective nootropic seriously. Upon further look, vinpocetine (a compound derived from the plant) is a cognitive protective agent that has hundreds of scientific references and ample supporting evidence.

European societies have extracted and used variants of vinpocetine for many years in order to act as a neuroprotective agent against toxins and support against inflammation [1]. It is also considered a useful combatant of age-related cognitive decline (such as dementia, Alzheimer’s disease etc) [2].

Most of the studies and evidence of vinpocetine is positive and focuses on cognition via reaction time, processing accuracy, and a variety of similar metrics. All of the studies suggest this potent extract is useful and quite safe as well.

Also Known As

Vincamine, Vinca Minor, Periwinkle Extract, Cavinton (Brand Name), ethyl apovincaminate

Editors’ Thoughts on Vinpocetine

I have never experienced vinpocetine alone, but I have taken it as part of other products. Namely, as part of Alpha Brain, which does not have an adequate dosage (according to sources, it is only half).

I can’t really say whether it was positive or negative, but Alpha Brain was effective (albeit a bit overpriced).

Mansal Denton, Nootropedia EditorVinpocetine

Benefits of Vinpocetine

The first and most often touted benefit of vinpocetine is for memory formation and learning. According to studies (measured by Sternberg assessment), patients recorded better working memory and reaction speed when taking various doses of vinpocetine [3]. Unlike many of the other nootropics and studies, this was also done on healthy adults (rather than elderly individuals already suffering from age related cognitive decline).

Vinpocetine benefits also include neuroprotective properties against cognitive decline. One study showed that vinpocetine could help reduce the impact of cognitive decline and concluded the drug did so through enhanced blood flow [4].

Finally, one of the main benefits of vinpocetine includes subjective well being enhancement. Elderly individuals who are suffering age related cognitive decline found that vinpocetine could help support them in their mood and feeling of happiness [5]. While more studies are needed on healthy adults in all of these vinpocetine benefits, this initial research looks promising.

How Does Vinpocetine Work?

Given the odd name and science of your brain, you may wonder “how does vinpocetine work?” and in scientific terms, this is called the “mechanism of action”. For vinpocetine, there are many mechanisms at play. One is that vinpocetine inhibits an enzyme called PDE1 [6], which helps improve blood flow to the brain. This has a host of benefits including more oxygen to certain regions that are responsible for cognition.

Another mechanism is that vinpocetine is able to influence neurotransmitter release through specific channels in the brain [7]. These neurotransmitters are useful for creating memories, learning, and a host of other benefits.

Side Effects of Vinpocetine

Unlike many other nootropics that don’t need much warning, vinpocetine is potentially dangerous depending on your personal biochemistry. After all, this is an extract of a plant that is synthetically derived and used at high potency for cognitive enhancement.

The number on side effect of vinpocetine to be concerned with is the blood pressure drop you might experience if using vinpocetine via I.V. However, most people take vinpocetine orally, which is not thought to create the reduction of white blood cells that is sometimes cited.

In general, vinpocetine side effects are few and far between. It is a well tolerated substance and is found in the most popular nootropic on the market (Alpha Brain by Onnit).

Vinpocetine Dosage

The daily recommended range for vinpocetine is around 15 – 60 mg, which is a large variation given the potency. It is probably best to start with 15 – 20 mg of the supplement before starting to get into higher doses. Keep in mind that this is over the course of 3 doses throughout the day, which are to be taken with meals.

The low dose of 5 mg each with your three meals for the day will be a great place to start, but 20 mg at each meal would be considered the dose for efficacy and neuroprotection. Like other nootropics, the dosage depends on your goals. 30 – 45 mg is considered a good dosage for cognition and memory formation while the lower range is for neuroprotective properties.

How and Where to Buy Vinpocetine

 

Periwinkle might be easier to find than vinpocetine in some brick and mortar locations, but there are many options online. Because it has grown in popularity as research has been published, vinpocetine has become a hot commodity included in many popular products, such as Alpha Brain. Their dosage includes 5 mg, but you may want to purchase vinpocetine in a higher volume.

For that, there are many vendors online that you can buy vinpocetine. Typically, it is best to find 5 – 10 mg capsules so that you can dose out as you need it throughout the day. While this nootropic does not require as much stringent testing (such as assay and heavy metals), we recommend you find a vendor that is willing to do these tests on at least some of their products.

When it comes to Vinpocetine, our most trusted source is PureNootropics, they have pure products and easy to follow instructions. Purchase Vinpocetine from PureNootropics here.

Selected Community Experiences

“The Vinpocetine that I got comes in 30mg tablets, which is a higher dose than I had intended for my stack, but I suspect I will survive. ANYWAY, took my dose, and about half an hour later, I felt like my head was going to explode for a while. It wasn't even a bad headache, really, but it was certainly uncomfortable. About an hour after taking it, though, my headache was completely gone, and I felt great.” [8] – djeik

“I love the effects of Vinpocetine, but it always lowers my immune function. I start to get sick 4-5 days after using it daily. The immune lowering effects are pretty well documented.” [9]- MisterYouAreSoDumb

References (Click to Expand)
  1. //www.ncbi.nlm.nih.gov/pubmed/20448200
  2. //www.ncbi.nlm.nih.gov/pubmed/21311488
  3. //www.ncbi.nlm.nih.gov/pubmed/3899677
  4. //www.ncbi.nlm.nih.gov/pubmed/21183904
  5. //www.ncbi.nlm.nih.gov/pubmed/21183904
  6. //www.ncbi.nlm.nih.gov/pubmed/6322804
  7. //www.ncbi.nlm.nih.gov/pubmed/10591410
  8. //www.reddit.com/r/Nootropics/comments/gaoq4/starting_noot_stack_saturday_tried_vinpocetine/
  9. //www.reddit.com/r/Nootropics/comments/3jppwe/bad_allergic_reaction_vinpocetine/

 

Other Scientific Resources (Click to Expand)
  1. //ntp-server.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/Vincamine.pdf
  2. //www.ncbi.nlm.nih.gov/pubmed/1037211
  3. //onlinelibrary.wiley.com/doi/10.1002/ardp.19833160709/abstract
  4. //www.ncbi.nlm.nih.gov/pubmed/21857073
  5. //www.ncbi.nlm.nih.gov/pubmed/11113577
  6. //www.ncbi.nlm.nih.gov/pubmed/17631470
  7. //onlinelibrary.wiley.com/doi/10.1002/jlac.199319930140/abstract
  8. //www.ncbi.nlm.nih.gov/pubmed/11985336
  9. //www.ncbi.nlm.nih.gov/pubmed/2624613
  10. //www.ncbi.nlm.nih.gov/pubmed/582791
  11. //www.ncbi.nlm.nih.gov/pubmed/22180371
  12. //www.ncbi.nlm.nih.gov/pubmed/1418055
  13. //www.ncbi.nlm.nih.gov/pubmed/19040178
  14. //www.ncbi.nlm.nih.gov/pubmed/19651165
  15. //www.ncbi.nlm.nih.gov/pubmed/3691609
  16. //www.ncbi.nlm.nih.gov/pubmed/16321580
  17. //www.ncbi.nlm.nih.gov/pubmed/3899662
  18. //www.ncbi.nlm.nih.gov/pubmed/21056658
  19. //www.ncbi.nlm.nih.gov/pubmed/12173017
  20. //www.ncbi.nlm.nih.gov/pubmed/2384112
  21. //www.ncbi.nlm.nih.gov/pubmed/16366040
  22. //www.ncbi.nlm.nih.gov/pubmed/10540601
  23. //www.ncbi.nlm.nih.gov/pubmed/12460136
  24. //www.ncbi.nlm.nih.gov/pubmed/12417394
  25. //www.balazs-gulyas.hu/pdf/2005/Szilagyi.pdf
  26. //www.sciencedirect.com/science/article/pii/S0378517398001690
  27. //www.ncbi.nlm.nih.gov/pubmed/2455529
  28. //www.ncbi.nlm.nih.gov/pubmed/10425362
  29. //www.ncbi.nlm.nih.gov/pubmed/2554921
  30. //www.ncbi.nlm.nih.gov/pubmed/6322804
  31. //www.ncbi.nlm.nih.gov/pubmed/191039
  32. //www.ncbi.nlm.nih.gov/pubmed/17697115
  33. //www.ncbi.nlm.nih.gov/pubmed/19853596
  34. //www.ncbi.nlm.nih.gov/pubmed/20219634
  35. //www.ncbi.nlm.nih.gov/pubmed/2176433
  36. //www.ncbi.nlm.nih.gov/pubmed/12730276
  37. //www.ncbi.nlm.nih.gov/pubmed/8957220
  38. //www.ncbi.nlm.nih.gov/pubmed/8957220
  39. //www.ncbi.nlm.nih.gov/pubmed/9665614
ShareTweetPinShare

STAY IN THE KNOW

Sign up for our exclusive newsletter to keep up
to date with the latest in nootropics and health optimization.
Previous Post

Ginkgo Biloba

Next Post

Alpha Brain Review [Updated 2019]

Nootropedia

Nootropedia

Nootropedia is meant to be a resource for individuals researching drugs and supplements that are good for brain health, otherwise known as nootropics, and thus we are the Nootropics Encyclopedia. Because of our in-depth coverage of this topic, our community has requested that we cover other brain health topics and "lifehacks" so that has become the focus of Nootropedia.

Related Posts

Akua Life Bottles
Blog

Akua Life Review: Neuro-Stack and Enlighten

October 22, 2019
kanna
Anxiety

Kanna (Sceletium tortuosum)

June 28, 2019
Apple Cider Vinegar
Alternative Solutions

Apple Cider Vinegar

June 27, 2019
Peppermint Plant
Anxiety

Peppermint Essential Oil

June 27, 2019
Lavender Essential Oil
Anxiety

Lavender Essential Oil

June 27, 2019
Celastrus Paniculatus: The Rediscovery of An Ancient Himalayan Nootropic
Anti-Oxidants

Celastrus Paniculatus: The Rediscovery of An Ancient Himalayan Nootropic

June 25, 2019
Load More
Next Post
alpha brain review

Alpha Brain Review [Updated 2019]

Recommended

Mind Lab Pro Review: 2 Major Red Flags (and Surprising Science)

Mind Lab Pro Review: 2 Major Red Flags (and Surprising Science)

3 years ago
Paul Stamets Epigenetic Neurogenesis Stack

Paul Stamets Epigenetic Neurogenesis Stack

2 years ago
gabapentin drug

Gabapentin High – Why Gabapentin Recreational Use is Exploding

4 years ago
Top 9 Best Nootropics of 2019 (Updated)

Four Sigmatic Review – What Tim Ferriss Didn’t Say About Mushroom Coffee

4 years ago

Don't Miss

Looking for general wellness tips?  A new website just launched you’ll want to see

Looking for general wellness tips? A new website just launched you’ll want to see

February 11, 2020
10 Ways to Manage Stress (Besides Meditation)

10 Ways to Manage Stress (Besides Meditation)

April 3, 2020
6 Supplements for Heartburn/Acid Reflux

6 Supplements for Heartburn/Acid Reflux

June 17, 2020
PEA (palmitoylethanolamide):  Benefits & What You Need to Know

PEA (palmitoylethanolamide): Benefits & What You Need to Know

March 17, 2020
Nootropedia

© 2019 - Optimized Mind dba Nootropedia.com

Quick Links

  • About
  • Affiliate Disclosure
  • Contact
  • Medical Disclaimer
  • Privacy Policy

Follow Us

No Result
View All Result
  • Nootropics
    • Racetams
    • Natural
    • Cholinergics
    • Unique Blends
  • Brain & Body Support
    • Cognitive Enhancers
    • Food & Nutrition
    • Anti-Oxidants
    • Nutrients & Minerals
    • Hormone Support
    • Inflammation & Immune
    • Fitness & Movement
  • Mood
    • Stress Relief
    • Herbs & Plants
    • Relaxation Strategies
  • Healthy Aging
    • Memory
    • Cellular Health
  • Alternative Solutions
    • Essential Oils
    • Anxiety
    • ADHD
    • Sleep Aids
  • Blog
    • Comparisons
    • Guides
    • How To

© 2019 - Optimized Mind dba Nootropedia.com