The Odyssey is one of the oldest and most influential historical tales of modern western civilization. Passed down through songs, it remains an important literary work, but may also hold the key to solving our current crisis with diabetes and metabolic syndrome.
The drug is commonly called galantamine and it's a popular nootropic and cognitive enhancer for many within the biohacking community. In Homer's Odyssey, the Greek god Hermes gives Odysseus the flower to protect him from Circe's magic (to prevent memory loss and delirium).
Galantamine isn't a new drug, but it's most commonly used for treating Alzheimer's disease as an acetylcholinesterase inhibitor. Recently, Dr. Valentin Pavlov at the Northwell Health's Feinstein Institute for Medical Research discovered galantamine could also reduce key markers of inflammation related to metabolic syndrome by up to 25%.
“What galantamine does is activate the nervous system to decrease inflammation” Dr. Yael Tobi Harris explains.
The recent study, published in JCI Insight found that galantamine helped increase the levels of anti-inflammatory molecules, reduced their levels of insulin, and even insulin resistance compared to the placebo group.
Can Galantamine Solve Metabolic Syndrome?
While a pill alone is not a comprehensive solution to metabolic syndrome or diabetes, it could be an added tool to combat these diseases. Because galantamine is already an FDA-approved drug, it will be far easier and cheaper to make it available for those suffering from metabolic syndrome. Whereas it usually takes millions of dollars and many years, galantamine is already approved and safe.
Even better, the doses used in this trial to treat metabolic syndrome were less than the highest approved dosage. Groups were given 8 mg and 16 mg of galantamine and both showed positive trends against markers of inflammation even though many elderly patients use up to 24 mg.
Within the past 5 years, numerous doctors and researchers have started viewing Alzheimer's disease as type 3 diabetes. Given that galantamine can reduce the symptoms of Alzheimer's disease (memory loss) and treat the inflammation that causes it, there is new hope for this FDA-approved drug.
The nootropics community has used galantamine for years to improve memory formation, learning ability, and especially for dream enhancement. While more research is needed, it seems the biohackers and self-experimenters may have gotten this one right.