Adrafinil vs. Modafinil: One of These is Better Than the Other

Summary

When comparing adrafinil vs. modafinil there are subtle differences between the two that have drastic consequences for the efficacy of the drug.

Modafinil is usually considered more effective than adrafinil.

This conclusion is based on adrafinil’s mechanism, which is to be converted by the liver into modafinil. Most people (including the French drug administration) believe the added stress to the liver to not be worth the risks.

Studies On Adrafinil vs. Modafinil

Most of the scientific research is currently done on modafinil. This does not mean adrafinil does not work. In fact, adrafinil works so well because modafinil is well-researched and understood. The main mechanism for adrafinil is to convert into modafinil through the liver process and then improve cognition.

Despite this process, there are slight differences between adrafinil and modafinil. To find out more about these differences, you must visit online communities such as Reddit and Longecity. The subjective experiences of people within these communities will teach you about the differences even though they must be taken with a grain of salt.

Either way, the evidence suggests that modafinil is a potent and useful cognitive enhancer. Studies show it is as powerful as amphetamine-based drugs for treating cognitive fatigue and mood degradation that comes from sleep deprivation [1].

Side Effects of Adrafinil and Modafinil

The potency of these drugs makes them susceptible to side effects as well. If you are taking adrafinil and modafinil, there may be feelings of irritability and anxiety or even nausea and gastrointestinal distress. Some people online complain (or laud) the appetite suppression that often comes from these types of nootropic drugs.

For adrafinil especially, the worry is that there will be side effects for the liver. People complain that by taking a drug that gets converted in the liver, it is problematic for the liver. While this might be a concern in theory, it will depend on the person. One Redditor did a liver test over time alongside adrafinil supplementation and found no differences in health. This may have been too short of a period and it was only a single sample, but is interesting nonetheless.

One Benefit of Adrafinil

One of the major benefits of adrafinil is the fact that it is still unregulated and considered legal. Most people do not realize that modafinil is technically a scheduled drug as it requires a prescription to take. While it is easy to purchase modafinil online, it is better that you get prescription to be safe within the bounds of the law.

However, adrafinil is unregulated and thus can be taken without any kind of documentation or prescription.

References (Click to Expand)
  1. http://www.ncbi.nlm.nih.gov/pubmed/10607161